My toenails grow slowly, so 2 weeks isn't enough time judge one way or another fairly. In fact, they seem to be growing slower while I'm treating them with the product. Since 9 of my 10 toes are affected, I just treat all of my toenails with the product. I hope to start seeing changes in another week or two.
FYI - I found that for me it was much easier to apply by removing the roll-on fitting and applying it with the tip of my finger.